Don't use the WAN accelerator (unless you have less than 5-10 Mbps connection)

Thankfully I don't have connections that are that slow but generally speaking the WAN accelerator (optimization) doesn't perform very well on the lower end devices that sites with slow WAN connections are more likely to have.  Feel free to chime in on your experience.  I may need to adjust my recommendation of 5-10 Mbps.